​研究内容

​研究業績(論文)

1: Kaga T, Kojima T, Yokoyama S, Sato H, Yoshida N, Ichikawa K. SUBRETINAL

ENDOSCOPIC SURGERY TO TREAT LARGE SUBRETINAL HEMORRHAGES SECONDARY TO AGE-RELATED MACULAR DEGENERATION. Retina. 2018 Jan 23. [Epub ahead of print]

 

2: Nakamura T, Isogai N, Kojima T, Yoshida Y, Sugiyama Y. Implantable Collamer Lens-sizing Method based on Swept Source Anterior Segment Optical Coherence Tomography. Am J Ophthalmol. 2017 Dec 30. [Epub ahead of print]

 

3: Kojima T, Takagi M, Ichikawa K, Horai R, Sakai Y, Tanaka Y, Tamaoki A, Ichikawa K. Clinical and ex vivo laboratory comparison of the self-sealing properties and dimensional stability between the femtosecond laser and manual

clear corneal incisions. Acta Ophthalmol. 2017 Nov 30. [Epub ahead of print]

 

4: Yokoyama S, Kojima T, Mori T, Matsuda T, Sato H, Yoshida N, Kaga T, Smith RT, Ichikawa K. Clinical outcomes of endoscope-assisted vitrectomy for treatment of rhegmatogenous retinal detachment. Clin Ophthalmol. 2017 Nov 14;11:2003-2010.

 

5: Tanaka Y, Yokoyama S, Horai R, Kojima T, Hiroyuki S, Kato Y, Takagi M, Nakamura H, Tanaka K, Ichikawa K, Tanabe S. Effect of Background Luminance Level on the Assessment of Color Visual Acuity Using Colored Landolt Rings in Young

Healthy Subjects. Curr Eye Res. 2017 Nov 22:1-7.

 

6: Kamiya K, Shimizu K, Igarashi A, Kitazawa Y, Kojima T, Nakamura T, Oka Y, Matsumoto R. Posterior chamber phakic intraocular lens implantation: comparative, multicentre study in 351 eyes with low-to-moderate or high myopia. Br J

Ophthalmol. 2018 Feb;102(2):177-181.

 

7: Takagi M, Kojima T, Ichikawa K, Tanaka Y, Kato Y, Horai R, Tamaoki A, Ichikawa K. Comparison of Maximum Stretch Forces between Femtosecond Laser-Assisted Capsulotomy and Continuous Curvilinear Capsulorhexis. J Ophthalmol.

2017;2017:3489373.

 

8: Kojima T, Hasegawa A, Nakamura T, Isogai N, Kataoka T, Ichikawa K. Five-Year PROSE Treatment for Aniridic Keratopathy. Optom Vis Sci. 2016 Oct;93(10):1328-1332. 

 

9: Kojima T, Dogru M, Ibrahim OM, Wakamatsu TH, Ito M, Igarashi A, Inaba T, Shimizu T, Shirasawa T, Shimazaki J, Tsubota K. Effects of Oxidative Stress on the Conjunctiva in Cu, Zn-Superoxide Dismutase-1 (Sod1)-Knockout Mice. Invest

Ophthalmol Vis Sci. 2015 Dec;56(13):8382-91.

 

10: Tamaoki A, Kojima T, Hasegawa A, Nakamura H, Tanaka K, Ichikawa K. Intraocular lens power calculation in cases with posterior keratoconus. J Cataract Refract Surg. 2015 Oct;41(10):2190-5.

 

11: Yokoyama S, Kojima T, Kaga T, Ichikawa K. Increased internal higher-order aberrations as a useful parameter for indication of vitrectomy in three asteroid hyalosis cases. BMJ Case Rep. 2015 Dec 23;2015. 

 

12: Kojima T, Dogru M, Higuchi A, Nagata T, Ibrahim OM, Inaba T, Tsubota K. The effect of Nrf2 knockout on ocular surface protection from acute tobacco smoke exposure: evidence from Nrf2 knockout mice. Am J Pathol. 2015 Mar;185(3):776-85.

 

13: Ibrahim OM, Dogru M, Kaido M, Kojima T, Fujishima H, Tsubota K. Functional visual acuity assessment of severe atopic keratoconjunctivitis. Cornea. 2014 Nov;33 Suppl 11:S13-8.

 

14: Kamiya K, Shimizu K, Kobashi H, Igarashi A, Komatsu M, Nakamura A, Kojima T, Nakamura T. Three-year follow-up of posterior chamber toric phakic intraocular lens implantation for the correction of high myopic astigmatism in eyes with

keratoconus. Br J Ophthalmol. 2015 Feb;99(2):177-83.

 

15: Ibrahim OM, Dogru M, Matsumoto Y, Igarashi A, Kojima T, Wakamatsu TH, Inaba T, Shimizu T, Shimazaki J, Tsubota K. Oxidative stress induced age dependent meibomian gland dysfunction in Cu, Zn-superoxide dismutase-1 (Sod1) knockout

mice. PLoS One. 2014 Jul 18;9(7):e99328.

 

16: Kojima T, Dogru M, Ibrahim OM, Nagata T, Higa K, Shimizu T, Shirasawa T, Satake Y, Shimazaki S, Shimazaki J, Tsubota K. The effects of 3% diquafosol sodium application on the tear functions and ocular surface of the Cu,Zn-superoxide dismutase-1 (Sod1)-knockout mice. Mol Vis. 2014 Jun 28;20:929-38.

 

17: Villani E, Baudouin C, Efron N, Hamrah P, Kojima T, Patel SV, Pflugfelder SC, Zhivov A, Dogru M. In vivo confocal microscopy of the ocular surface: from bench to bedside. Curr Eye Res. 2014 Mar;39(3):213-31.

 

18: Kojima T, Matsumoto Y, Ibrahim OM, Wakamatsu TH, Dogru M, Tsubota K. Evaluation of a thermosensitive atelocollagen punctal plug treatment for dry eye disease. Am J Ophthalmol. 2014 Feb;157(2):311-317.

 

19: Ohguchi T, Kojima T, Ibrahim OM, Nagata T, Shimizu T, Shirasawa T, Kawakita T, Satake Y, Tsubota K, Shimazaki J, Ishida S. The effects of 2% rebamipide ophthalmic solution on the tear functions and ocular surface of the superoxide

dismutase-1 (sod1) knockout mice. Invest Ophthalmol Vis Sci. 2013 Nov 21;54(12):7793-802.

 

20: Dumbleton K, Caffery B, Dogru M, Hickson-Curran S, Kern J, Kojima T, Morgan PB, Purslow C, Robertson DM, Nelson JD; members of the TFOS International Workshop on Contact Lens Discomfort. The TFOS International Workshop on Contact Lens Discomfort: report of the subcommittee on epidemiology. Invest Ophthalmol Vis Sci. 2013 Oct 18;54(11):TFOS20-36.

 

21: Kaido M, Uchino M, Kojima T, Dogru M, Tsubota K. Effects of diquafosol tetrasodium administration on visual function in short break-up time dry eye. J Ocul Pharmacol Ther. 2013 Jul-Aug;29(6):595-603.

 

 

22: Hara S, Kojima T, Dogru M, Uchino Y, Goto E, Matsumoto Y, Kawakita T, Tsubota K, Shimazaki J. The impact of tear functions on visual outcome following keratoplasty in eyes with keratoconus. Graefes Arch Clin Exp Ophthalmol. 2013

Jul;251(7):1763-70.

 

23: Hirayama M, Murat D, Liu Y, Kojima T, Kawakita T, Tsubota K. Efficacy of a novel moist cool air device in office workers with dry eye disease. Acta Ophthalmol. 2013 Dec;91(8):756-62.

 

24: Wakamatsu TH, Dogru M, Matsumoto Y, Kojima T, Kaido M, Ibrahim OM, Sato EA, Igarashi A, Ichihashi Y, Satake Y, Shimazaki J, Tsubota K. Evaluation of lipid oxidative stress status in Sjögren syndrome patients. Invest Ophthalmol Vis Sci.

2013 Jan 7;54(1):201-10.

 

25: Chung JS, Tomihari M, Tamura K, Kojima T, Cruz PD Jr, Ariizumi K. The DC-HIL ligand syndecan-4 is a negative regulator of T-cell allo-reactivity responsible for graft-versus-host disease. Immunology. 2013 Feb;138(2):173-82.

 

26: Tsubota K, Kawashima M, Inaba T, Dogru M, Matsumoto Y, Ishida R, Kaido M, Kojima T, Uchino M, Uchino Y, Ogawa Y, Nakamura S, Higuchi A, Shinmura K, Watanabe M, Kawakita T. The antiaging approach for the treatment of dry eye.

Cornea. 2012 Nov;31 Suppl 1:S3-8.

 

27: Ibrahim OM, Dogru M, Kojima T, Matsumoto Y, Wakamatsu TH, Tsubota K, Fujishima H. OCT assessment of tear meniscus after punctal occlusion in dry eye disease. Optom Vis Sci. 2012 May;89(5):E770-6.

 

28: Kojima T, Wakamatsu TH, Dogru M, Ogawa Y, Igarashi A, Ibrahim OM, Inaba T, Shimizu T, Noda S, Obata H, Nakamura S, Wakamatsu A, Shirasawa T, Shimazaki J, Negishi K, Tsubota K. Age-related dysfunction of the lacrimal gland and oxidative stress: evidence from the Cu,Zn-superoxide dismutase-1 (Sod1) knockout mice. Am J Pathol. 2012 May;180(5):1879-96.

 

29: Ibrahim OM, Kojima T, Wakamatsu TH, Dogru M, Matsumoto Y, Ogawa Y, Ogawa J, Negishi K, Shimazaki J, Sakamoto Y, Sasaki H, Tsubota K. Corneal and retinal effects of ultraviolet-B exposure in a soft contact lens mouse model. Invest

Ophthalmol Vis Sci. 2012 Apr 30;53(4):2403-13.

 

30: Mori T, Yokoyama S, Kojima T, Isogai N, Ito M, Horai R, Nakamura T, Ichikawa K. Factors affecting rotation of a posterior chamber collagen copolymer toric phakic intraocular lens. J Cataract Refract Surg. 2012 Apr;38(4):568-73.

 

31: Hasegawa A, Kojima T, Isogai N, Tamaoki A, Nakamura T, Ichikawa K. Astigmatism correction: Laser in situ keratomileusis versus posterior chamber collagen copolymer toric phakic intraocular lens implantation. J Cataract Refract

Surg. 2012 Apr;38(4):574-81.

 

32: Jain S, De la Cruz J, Kang E, Kojima T, Chang JH, Kim JY. Expression of phosphorylated heat shock protein 27 during corneal epithelial wound healing. Cornea. 2012 Jul;31(7):820-7.

 

33: Kojima T, Yokoyama S, Ito M, Horai R, Hara S, Nakamura T, Ichikawa K. Optimization of an implantable collamer lens sizing method using high-frequency ultrasound biomicroscopy. Am J Ophthalmol. 2012 Apr;153(4):632-7, 637.e1.

 

34: Kojima T, Matsumoto Y, Ibrahim OM, Wakamatsu TH, Uchino M, Fukagawa K, Ogawa J, Dogru M, Negishi K, Tsubota K. Effect of controlled adverse chamber environment exposure on tear functions in silicon hydrogel and hydrogel soft

contact lens wearers. Invest Ophthalmol Vis Sci. 2011 Nov 11;52(12):8811-7.

 

35: Kojima T, Ibrahim OM, Wakamatsu T, Tsuyama A, Ogawa J, Matsumoto Y, Dogru M, Tsubota K. The impact of contact lens wear and visual display terminal work on ocular surface and tear functions in office workers. Am J Ophthalmol. 2011

Dec;152(6):933-940.

 

36: Kojima T, Watabe T, Nakamura T, Ichikawa K, Satoh Y. Effects of preoperative punctal plug treatment on visual function and wound healing in laser epithelial keratomileusis. J Refract Surg. 2011 Dec;27(12):894-8.

 

37: Hara S, Kojima T, Ishida R, Goto E, Matsumoto Y, Kaido M, Shimazaki J, Dogru M, Tsubota K. Evaluation of tear stability after surgery for conjunctivochalasis. Optom Vis Sci. 2011 Sep;88(9):1112-8.

 

38: Yokoyama S, Kojima T, Horai R, Ito M, Nakamura T, Ichikawa K. Repeatability of the ciliary sulcus-to-sulcus diameter measurement using wide-scanning-field ultrasound biomicroscopy. J Cataract Refract Surg. 2011 Jul;37(7):1251-6.

 

39: Kojima T, Hasegawa A, Hara S, Horai R, Yoshida Y, Nakamura T, Dogru M, Ichikawa K. Quantitative evaluation of night vision and correlation of refractive

and topographical parameters with glare after orthokeratology. Graefes Arch Clin

Exp Ophthalmol. 2011 Oct;249(10):1519-26.

 

40: Wakamatsu TH, Yamaguchi T, Negishi K, Kaido M, Matsumoto Y, Ishida R, Kojima T, Ibrahim OM, Saiki M, Dogru M, Tsubota K. Functional visual acuity after neodymium:YAG laser capsulotomy in patients with posterior capsule opacification

and good visual acuity preoperatively. J Cataract Refract Surg. 2011 Feb;37(2):258-64.

 

41: Dogru M, Ward SK, Wakamatsu T, Ibrahim O, Schnider C, Kojima T, Matsumoto Y, Ogawa J, Shimazaki J, Tsubota K. The effects of 2 week senofilcon-A silicone hydrogel contact lens daily wear on tear functions and ocular surface health

status. Cont Lens Anterior Eye. 2011 Apr;34(2):77-82.

 

42: Ibrahim OM, Dogru M, Ward SK, Matsumoto Y, Wakamatsu TH, Ishida K, Tsuyama A, Kojima T, Shimazaki J, Tsubota K. The efficacy, sensitivity, and specificity of strip meniscometry in conjunction with tear function tests in the assessment of

tear meniscus. Invest Ophthalmol Vis Sci. 2011 Apr 6;52(5):2194-8.

 

43: Hara S, Hazama A, Miyake M, Kojima T, Sasaki Y, Shimazaki J, Dogru M, Tsubota K. The effect of topical amiloride eye drops on tear quantity in rabbits. Mol Vis. 2010 Nov 4;16:2279-85.

 

44: Kojima T, Matsumoto Y, Dogru M, Tsubota K. The application of in vivo laser scanning confocal microscopy as a tool of conjunctival in vivo cytology in the diagnosis of dry eye ocular surface disease. Mol Vis. 2010 Nov 19;16:2457-64.

 

45: Matsumoto Y, Murat D, Kojima T, Shimazaki J, Tsubota K. The comparison of solitary topical micafungin or fluconazole application in the treatment of Candida fungal keratitis. Br J Ophthalmol. 2011 Oct;95(10):1406-9.

 

46: Kojima T, Ishida R, Sato EA, Kawakita T, Ibrahim OM, Matsumoto Y, Kaido M, Dogru M, Tsubota K. In vivo evaluation of ocular demodicosis using laser scanning confocal microscopy. Invest Ophthalmol Vis Sci. 2011 Feb 1;52(1):565-9.

 

47: Kojima T, Maeda M, Yoshida Y, Ito M, Nakamura T, Hara S, Ichikawa K. Posterior chamber phakic implantable collamer lens: changes in vault during 1 year. J Refract Surg. 2010 May;26(5):327-32.

 

48: Kojima T, Horai R, Hara S, Nakamura H, Nakamura T, Satoh Y, Ichikawa K. Correction of residual refractive error in pseudophakic eyes with the use of a secondary piggyback toricImplantable Collamer Lens. J Refract Surg. 2010

Oct;26(10):766-9.

 

49: Kojima T, Tamaoki A, Yoshida N, Kaga T, Suto C, Ichikawa K. Evaluation of axial length measurement of the eye using partial coherence interferometry and ultrasound in cases of macular disease. Ophthalmology. 2010 Sep;117(9):1750-4.

 

50: Kojima T, Matsumoto Y, Ibrahim OM, Sato EA, Dogru M, Tsubota K. In vivo evaluation of superior limbic keratoconjunctivitis using laser scanning confocal microscopy and conjunctival impression cytology. Invest Ophthalmol Vis Sci. 2010 Aug;51(8):3986-92.

 

51: Ward SK, Dogru M, Wakamatsu T, Ibrahim O, Matsumoto Y, Kojima T, Sato EA, Ogawa J, Schnider C, Negishi K, Tsubota K. Passive cigarette smoke exposure and soft contact lens wear. Optom Vis Sci. 2010 May;87(5):367-72.

 

52: Mimura T, Han KY, Onguchi T, Chang JH, Kim TI, Kojima T, Zhou Z, Azar DT. MT1-MMP-mediated cleavage of decorin in corneal angiogenesis. J Vasc Res. 2009;46(6):541-50.

 

53: Azar DT, Ghanem RC, de la Cruz J, Hallak JA, Kojima T, Al-Tobaigy FM, Jain S. Thin-flap (sub-Bowman keratomileusis) versus thick-flap laser in situ keratomileusis for moderate to high myopia: case-control analysis. J Cataract

Refract Surg. 2008 Dec;34(12):2073-8.

 

54: Kojima T, Higuchi A, Goto E, Matsumoto Y, Dogru M, Tsubota K. Autologous serum eye drops for the treatment of dry eye diseases. Cornea. 2008 Sep;27 Suppl 1:S25-30.

 

55: Kojima T, Azar DT, Chang JH. Neostatin-7 regulates bFGF-induced corneal lymphangiogenesis. FEBS Lett. 2008 Jul 23;582(17):2515-20.

 

56: Kojima T, Hallak JA, Azar DT. Control-matched analysis of laser in situ keratomileusis outcomes in high myopia. J Cataract Refract Surg. 2008 Apr;34(4):544-50.

 

57: Savini G, Prabhawasat P, Kojima T, Grueterich M, Espana E, Goto E. The challenge of dry eye diagnosis. Clin Ophthalmol. 2008 Mar;2(1):31-55.

 

58: Yoshida Y, Nakamura T, Hara S, Yoshida N, Kojima T, Ichikawa K. Topography-guided custom ablation for irregular corneal astigmatism using the NIDEK NAVEX Laser System. J Refract Surg. 2008 Jan;24(1):24-32.

 

59: Kojima T, Chung TY, Chang JH, Sayegh R, Casanova FH, Azar DT. Comparison of EphA receptor tyrosine kinases and ephrinA ligand expression to EphB-ephrinB in vascularized corneas. Cornea. 2007 Jun;26(5):569-78.

 

60: Goto E, Matsumoto Y, Kamoi M, Endo K, Ishida R, Dogru M, Kaido M, Kojima T, Tsubota K. Tear evaporation rates in Sjögren syndrome and non-Sjögren dry eye patients. Am J Ophthalmol. 2007 Jul;144(1):81-85.

 

61: Kojima T, Chang JH, Azar DT. Proangiogenic role of ephrinB1/EphB1 in basic fibroblast growth factor-induced corneal angiogenesis. Am J Pathol. 2007 Feb;170(2):764-73.

 

62: Goto E, Ishida R, Kaido M, Dogru M, Matsumoto Y, Kojima T, Tsubota K. Optical aberrations and visual disturbances associated with dry eye. Ocul Surf. 2006 Oct;4(4):207-13.

 

63: Matsumoto Y, Dogru M, Goto E, Ishida R, Kojima T, Onguchi T, Yagi Y, Shimazaki J, Tsubota K. Efficacy of a new warm moist air device on tear functions of patients with simple meibomian gland dysfunction. Cornea. 2006 Jul;25(6):644-50.

 

64: Dogru M, Ishida K, Matsumoto Y, Goto E, Ishioka M, Kojima T, Goto T, Saeki M, Tsubota K. Strip meniscometry: a new and simple method of tear meniscus evaluation. Invest Ophthalmol Vis Sci. 2006 May;47(5):1895-901.

 

65: Kojima T, Dogru M, Ishida R, Goto E, Matsumoto Y, Tsubota K. Clinical evaluation of the Smart Plug in the treatment of dry eyes. Am J Ophthalmol. 2006 Feb;141(2):386-8.

 

66: Ishida R, Kojima T, Dogru M, Kaido M, Matsumoto Y, Tanaka M, Goto E, Tsubota K. The application of a new continuous functional visual acuity measurement system in dry eye syndromes. Am J Ophthalmol. 2005 Feb;139(2):253-8.

 

67: Kojima T, Ishida R, Dogru M, Goto E, Matsumoto Y, Kaido M, Tsubota K. The effect of autologous serum eyedrops in the treatment of severe dry eye disease: a prospective randomized case-control study. Am J Ophthalmol. 2005

Feb;139(2):242-6.

 

68: Kojima T, Dogru M, Matsumoto Y, Goto E, Tsubota K. Tear film and ocular surface abnormalities after eyelid tattooing. Ophthal Plast Reconstr Surg. 2005 Jan;21(1):69-71.

 

69: Matsumoto Y, Dogru M, Goto E, Ohashi Y, Kojima T, Ishida R, Tsubota K. Autologous serum application in the treatment of neurotrophic keratopathy. Ophthalmology. 2004 Jun;111(6):1115-20.

 

70: Dogru M, Karakaya H, Baykara M, Ozmen A, Koksal N, Goto E, Matsumoto Y, Kojima T, Shimazaki J, Tsubota K. Tear function and ocular surface findings in premature and term babies. Ophthalmology. 2004 May;111(5):901-5.

 

71: Kojima T, Ishida R, Dogru M, Goto E, Takano Y, Matsumoto Y, Kaido M, Ohashi Y, Tsubota K. A new noninvasive tear stability analysis system for the assessment of dry eyes. Invest Ophthalmol Vis Sci. 2004 May;45(5):1369-74.

 

72: Ohashi Y, Ishida R, Kojima T, Goto E, Matsumoto Y, Watanabe K, Ishida N, Nakata K, Takeuchi T, Tsubota K. Abnormal protein profiles in tears with dry eye syndrome. Am J Ophthalmol. 2003 Aug;136(2):291-9.

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